5n7f

X-ray diffraction
2.3Å resolution

MAGI-1 complexed with a pRSK1 peptide

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
monomeric
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Annexin A2; Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 427 amino acids
Theoretical weight: 48.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P07355 (Residues: 22-339; Coverage: 94%)
  • Canonical: Q96QZ7 (Residues: 454-558; Coverage: 7%)
Gene names: AIP3, ANX2, ANX2L4, ANXA2, BAIAP1, BAP1, CAL1H, LPC2D, MAGI1, TNRC19
Sequence domains:
Ribosomal protein S6 kinase alpha-1 Chain: C
Molecule details ›
Chain: C
Length: 49 amino acids
Theoretical weight: 5.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15418 (Residues: 688-735; Coverage: 7%)
Gene names: MAPKAPK1A, RPS6KA1, RSK1

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Unit cell:
a: 60.15Å b: 98.56Å c: 200.31Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.189 0.186 0.24
Expression system: Escherichia coli