› 5n78

X-ray diffraction
2.85Å resolution

Crystal structure of the cytosolic domain of the CorA Mg2+ channel from Escherichia coli in complex with magnesium and cobalt hexammine

Released:
DOI: 10.2210/pdb5n78/pdb
PDB entry 5n78 coloured by chain, front view.
PDB entry 5n78 coloured by chain, side view.
PDB entry 5n78 coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
Structure and Cooperativity of the Cytosolic Domain of the CorA Mg2+ Channel from Escherichia coli.
Lerche M, Sandhu H, Flöckner L, Högbom M, Rapp M
Structure 25 1175-1186.e4 (2017)
PMID: 28669631

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142170 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Magnesium transport protein CorA Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 257 amino acids
Theoretical weight: 29.87 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0ABI4 (Residues: 1-257; Coverage: 81%)
Gene names: JW3789, b3816, corA
Sequence domains: CorA-like Mg2+ transporter protein

Ligands and Environments

3 bound ligands:
Ligand MG 6 x MG
Ligand NCO 14 x NCO
Ligand PG0 3 x PG0
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P21
Unit cell:
a: 73.721Å b: 117.316Å c: 91.858Å
α: 90° β: 103.14° γ: 90°
R-values:
R R work R free
0.18 0.178 0.218
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Structural and functional comparison of magnesium transporters throughout evolution.
Franken et al. (2022)
1 more