PDBe 5n3m

X-ray diffraction
1.23Å resolution

cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule D-arginine

Released:
Source organism: Cricetulus griseus
Entry authors: Siefker C, Heine A, Klebe G

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
cAMP-dependent protein kinase catalytic subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 353 amino acids
Theoretical weight: 41.19 KDa
Source organism: Cricetulus griseus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P25321 (Residues: 1-351; Coverage: null%)
Gene name: PRKACA
Sequence domains: Protein kinase domain

Ligands and Environments

3 bound ligands:

2 modified residues:

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P212121
Unit cell:
a: 51.979Å b: 71.002Å c: 97.552Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.14 0.139 0.164
Expression system: Escherichia coli BL21(DE3)