5myd

X-ray diffraction
2.3Å resolution

Convergent evolution involving dimeric and trimeric dUTPases in signalling.

Released:

Function and Biology Details

Reaction catalysed:
dUTP + H(2)O = dUMP + diphosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
dUTPase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 207 amino acids
Theoretical weight: 24.16 KDa
Source organism: Staphylococcus sp. HMSC068C09
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: A0A2D0TC86 (Residues: 1-187; Coverage: 100%)
Gene name: HMPREF2930_08375
Sequence domains: dUTPase

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04, ALBA BEAMLINE XALOC
Spacegroup: P21
Unit cell:
a: 69.89Å b: 81.44Å c: 81.53Å
α: 90° β: 106.92° γ: 90°
R-values:
R R work R free
0.226 0.224 0.265
Expression system: Escherichia coli BL21