› 5mwt

X-ray diffraction
1.71Å resolution

Galectin-1 in Complex with Ligand JB97

Released:
DOI: 10.2210/pdb5mwt/pdb
PDB 5mwt coloured by chain and viewed from the front.
PDB 5mwt coloured by chain and viewed from the side.
PDB 5mwt coloured by chain and viewed from the top.
Source organism: Homo sapiens
Entry authors: Grimm C, Bechold J

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Galectin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 133 amino acids
Theoretical weight: 14.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09382 (Residues: 3-135; Coverage: 99%)
Gene name: LGALS1
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

3 bound ligands:
Ligand BME 1 x BME
Ligand JB9 2 x JB9
Ligand SO4 1 x SO4
1 modified residue:
Ligand CME 6 x CME

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID30B
Spacegroup: P212121
Unit cell:
a: 43.29Å b: 58.25Å c: 111.24Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.205 0.232
Expression system: Escherichia coli

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