› 5mr2

X-ray diffraction
2.5Å resolution

Crystal structure of red abalone VERL repeat 2 with linker at 2.5 A resolution

Released:
DOI: 10.2210/pdb5mr2/pdb
PDB entry 5mr2 coloured by chain, front view.
PDB entry 5mr2 coloured by chain, side view.
PDB entry 5mr2 coloured by chain, top view.
Source organism: Haliotis rufescens
Primary publication:
Structural Basis of Egg Coat-Sperm Recognition at Fertilization.
Raj I, Sadat Al Hosseini H, Dioguardi E, Nishimura K, Han L, Villa A, de Sanctis D, Jovine L
Cell 169 1315-1326.e17 (2017)
PMID: 28622512

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186685 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Vitelline envelope sperm lysin receptor Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 134 amino acids
Theoretical weight: 15.09 KDa
Source organism: Haliotis rufescens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q8WR62 (Residues: 176-298; Coverage: 3%)
Gene name: VERL
Sequence domains: Vitelline envelope receptor for lysin

Ligands and Environments

1 bound ligand:
Ligand NAG 3 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: C2
Unit cell:
a: 69.92Å b: 79.19Å c: 81.24Å
α: 90° β: 102.62° γ: 90°
R-values:
R R work R free
0.239 0.234 0.28
Expression system: Homo sapiens

Quick links

Citations

9 review citations

The hallmarks of cell-cell fusion.
Hernández et al. (2017)
8 more

1 mention without citation

Structural Basis of Egg Coat-Sperm Recognition at Fertilization.
Raj et al. (2017)