X-ray diffraction
3.1Å resolution

G307E variant of murine Apoptosis Inducing Factor in complex with NAD+


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Apoptosis-inducing factor 1, mitochondrial Chains: A, C
Molecule details ›
Chains: A, C
Length: 535 amino acids
Theoretical weight: 58.4 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q9Z0X1 (Residues: 78-612; Coverage: 87%)
Gene names: Aif, Aifm1, Pdcd8
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P212121
Unit cell:
a: 73.43Å b: 116.78Å c: 166.48Å
α: 90° β: 90° γ: 90°
R R work R free
0.201 0.198 0.263
Expression system: Escherichia coli BL21(DE3)