5me8

X-ray diffraction
3.2Å resolution

N-terminal domain of the human tumor suppressor ING5

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-186799 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Inhibitor of growth protein 5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 107 amino acids
Theoretical weight: 12.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8WYH8 (Residues: 1-105; Coverage: 44%)
Gene name: ING5
Sequence domains: Inhibitor of growth proteins N-terminal histone-binding

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALBA BEAMLINE XALOC
Spacegroup: P6522
Unit cell:
a: 135.63Å b: 135.63Å c: 96.67Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.213 0.211 0.248
Expression system: Escherichia coli BL21(DE3)