5m72

X-ray diffraction
1.6Å resolution

Structure of the human SRP68-72 protein-binding domain complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Signal recognition particle subunit SRP72 Chain: A
Molecule details ›
Chain: A
Length: 160 amino acids
Theoretical weight: 18.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O76094 (Residues: 10-166; Coverage: 23%)
Gene name: SRP72
Sequence domains: Putative TPR-like repeat
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
Signal recognition particle subunit SRP68 Chain: B
Molecule details ›
Chain: B
Length: 71 amino acids
Theoretical weight: 8.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UHB9 (Residues: 546-614; Coverage: 11%)
Gene name: SRP68

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: C2
Unit cell:
a: 66.597Å b: 52.269Å c: 62.863Å
α: 90° β: 118.22° γ: 90°
R-values:
R R work R free
0.145 0.142 0.184
Expression system: Escherichia coli