5lx9

X-ray diffraction
2.4Å resolution

CRYSTAL STRUCTURE OF HUMAN ADIPONECTIN RECEPTOR 2 IN COMPLEX WITH A C18 FREE FATTY ACID AT 2.4 ANGSTROM RESOLUTION

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Adiponectin receptor protein 2 Chain: A
Molecule details ›
Chain: A
Length: 307 amino acids
Theoretical weight: 35.02 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q86V24 (Residues: 99-386; Coverage: 75%)
Gene names: ADIPOR2, PAQR2
Sequence domains: Haemolysin-III related
single-chain variable fragment Chain: H
Molecule details ›
Chain: H
Length: 284 amino acids
Theoretical weight: 29.84 KDa
Source organism: Mus musculus
Expression system: Drosophila melanogaster

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID30B
Unit cell:
a: 74.578Å b: 101.128Å c: 111.577Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 0.181 0.205
Expression systems:
  • Spodoptera frugiperda
  • Drosophila melanogaster