5lwy

X-ray diffraction
2.4Å resolution

Revised crystal structure of the human adiponectin receptor 2 in complex with a C18 free fatty acid

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
Non-polymer only trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Adiponectin receptor protein 2 Chain: A
Molecule details ›
Chain: A
Length: 292 amino acids
Theoretical weight: 33.1 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q86V24 (Residues: 100-386; Coverage: 74%)
Gene names: ADIPOR2, PAQR2
Sequence domains: Haemolysin-III related
V REGION HEAVY CHAIN Chain: H
Molecule details ›
Chain: H
Length: 119 amino acids
Theoretical weight: 13.16 KDa
Source organism: Mus musculus
Expression system: Drosophila melanogaster
Structure domains: Immunoglobulins
V REGION LIGHT CHAIN Chain: L
Molecule details ›
Chain: L
Length: 107 amino acids
Theoretical weight: 11.65 KDa
Source organism: Mus musculus
Expression system: Drosophila melanogaster
Structure domains: Immunoglobulins

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL32XU
Unit cell:
a: 74.58Å b: 101.03Å c: 108.63Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.198 0.224
Expression systems:
  • Trichoplusia ni
  • Drosophila melanogaster