PDBe 5lk5

X-ray diffraction
2.3Å resolution

Crystal structure of the globular domain of human calreticulin mutant D71K

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo decamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calreticulin Chains: A, B, C, D, E, F, G, H, I, J
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J
Length: 265 amino acids
Theoretical weight: 30.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: P27797 (Residues: 18-204, 303-368; Coverage: 63%)
Gene names: CALR, CRTC
Structure domains: Jelly Rolls

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P42
Unit cell:
a: 196.976Å b: 196.976Å c: 67.806Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.21 0.247
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'