X-ray diffraction
2.4Å resolution

Crystal structure of HDAC-like protein from P. aeruginosa in complex with a photo-switchable inhibitor.


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Histone deacetylase-like amidohydrolase Chains: A, B
Molecule details ›
Chains: A, B
Length: 380 amino acids
Theoretical weight: 41.1 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q9HXM1 (Residues: 1-380; Coverage: 100%)
Gene name: PA3774
Sequence domains: Histone deacetylase domain
Structure domains: Histone deacetylase domain

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P41212
Unit cell:
a: 82.19Å b: 82.19Å c: 217.03Å
α: 90° β: 90° γ: 90°
R R work R free
0.227 0.225 0.27
Expression system: Escherichia coli BL21(DE3)