5l7k

X-ray diffraction
2.1Å resolution

The crystal structure of myristoylated NPHP3 peptide in complex with UNC119a

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
monomeric
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein unc-119 homolog A Chains: A, G
Molecule details ›
Chains: A, G
Length: 180 amino acids
Theoretical weight: 21.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13432 (Residues: 58-237; Coverage: 75%)
Gene names: RG4, UNC119
Sequence domains: GMP-PDE, delta subunit
Structure domains: GMP phosphodiesterase, delta subunit
Nephrocystin-3 Chain: B
Molecule details ›
Chain: B
Length: 6 amino acids
Theoretical weight: 535 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q7Z494 (Residues: 2-7; Coverage: 1%)
Gene names: KIAA2000, NPHP3

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: I41
Unit cell:
a: 88.27Å b: 88.27Å c: 105.94Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.216 0.278
Expression systems:
  • Escherichia coli
  • Not provided