› 5l5g

X-ray diffraction
10Å resolution

Plexin A2 full extracellular region, domains 1 to 8 modeled, data to 10 angstrom

Released:
DOI: 10.2210/pdb5l5g/pdb
PDB entry 5l5g coloured by chain, front view.
PDB entry 5l5g coloured by chain, side view.
PDB entry 5l5g coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural Basis for Plexin Activation and Regulation.
Kong Y, Janssen BJ, Malinauskas T, Vangoor VR, Coles CH, Kaufmann R, Ni T, Gilbert RJ, Padilla-Parra S, Pasterkamp RJ, Jones EY
Neuron 91 548-60 (2016)
PMID: 27397516

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159715 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Plexin-A2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 1212 amino acids
Theoretical weight: 133.58 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: P70207 (Residues: 33-1231; Coverage: 64%)
Gene names: Kiaa0463, Plxna2
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P3221
Unit cell:
a: 238.4Å b: 238.4Å c: 642.18Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.337 0.335 0.37
Expression system: Homo sapiens

Quick links

Citations

14 review citations

Macrophage Clearance of Apoptotic Cells: A Critical Assessment.
Gordon et al. (2018)
13 more

2 mentions without citation

Evolution and Diversity of Semaphorins and Plexins in Choanoflagellates.
Junqueira Alves et al. (2021)
1 more