› 5l4t

X-ray diffraction
1.9Å resolution

Crystal structure of FimH lectin domain in complex with 2-Deoxy-Heptylmannoside

Released:
DOI: 10.2210/pdb5l4t/pdb
PDB 5l4t coloured by chain and viewed from the front.
PDB 5l4t coloured by chain and viewed from the side.
PDB 5l4t coloured by chain and viewed from the top.
Source organism: Escherichia coli K-12
Entry authors: Jakob RP, Zihlmann P, Rabbani S, Maier T, Ernst B

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Type 1 fimbrin D-mannose specific adhesin Chains: A, B
Molecule details ›
Chains: A, B
Length: 158 amino acids
Theoretical weight: 16.92 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P08191 (Residues: 22-179; Coverage: 57%)
Gene names: JW4283, b4320, fimH
Sequence domains: FimH, mannose binding
Structure domains: Fimbrial-type adhesion domain

Ligands and Environments

1 bound ligand:
Ligand 6LS 2 x 6LS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Unit cell:
a: 67.76Å b: 68.57Å c: 96.11Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.2 0.218
Expression system: Escherichia coli BL21(DE3)

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