X-ray diffraction
1.95Å resolution

polyketide ketoreductase SimC7 - binary complex with NADP+


Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
NAD(P)-binding domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 304 amino acids
Theoretical weight: 32.28 KDa
Source organism: Streptomyces antibioticus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: G9VYV4 (Residues: 1-284; Coverage: 100%)
Gene name: simC7
Sequence domains: NAD(P)H-binding
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P41212
Unit cell:
a: 52.23Å b: 52.23Å c: 214Å
α: 90° β: 90° γ: 90°
R R work R free
0.183 0.182 0.217
Expression system: Escherichia coli BL21(DE3)