PDBe 5l13

X-ray diffraction
2.4Å resolution

Structure of ALDH2 in complex with 2P3

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aldehyde dehydrogenase, mitochondrial Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 517 amino acids
Theoretical weight: 56.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05091 (Residues: 1-517; Coverage: 100%)
Gene names: ALDH2, ALDM
Sequence domains: Aldehyde dehydrogenase family
Structure domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 99.412Å b: 127.049Å c: 294.847Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.158 0.155 0.206
Expression system: Escherichia coli