› 5kzq

X-ray diffraction
2.8Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Metabotropic glutamate receptor 2 Chain: A
Molecule details ›
Chain: A
Length: 570 amino acids
Theoretical weight: 63.31 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q14416 (Residues: 1-564; Coverage: 64%)
Gene names: GPRC1B, GRM2, MGLUR2
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand 6YS 1 x 6YS
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P41212
Unit cell:
a: 166.297Å b: 166.297Å c: 79.776Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.208 0.245
Expression system: Spodoptera frugiperda

Quick links

Citations

4 review citations

International Union of Basic and Clinical Pharmacology. CVIII. Calcium-Sensing Receptor Nomenclature, Pharmacology, and Function.
Leach et al. (2020)
3 more