X-ray diffraction
2.8Å resolution

Crystal Structure of Inward Rectifier Kir2.2 K62W Mutant In Complex with PIP2


Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
ATP-sensitive inward rectifier potassium channel 12 Chain: A
Molecule details ›
Chain: A
Length: 343 amino acids
Theoretical weight: 39.42 KDa
Source organism: Gallus gallus
Expression system: Komagataella pastoris
  • Canonical: F1NHE9 (Residues: 38-369; Coverage: 77%)
Gene name: KCNJ12
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: I4
Unit cell:
a: 81.303Å b: 81.303Å c: 183.572Å
α: 90° β: 90° γ: 90°
R R work R free
0.201 0.198 0.258
Expression system: Komagataella pastoris