X-ray diffraction
1.6Å resolution

Human mitochondrial calcium uniporter (residues 72-189) crystal structure with magnesium.


Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Calcium uniporter protein, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 124 amino acids
Theoretical weight: 13.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q8NE86 (Residues: 72-189; Coverage: 34%)
Gene names: C10orf42, CCDC109A, MCU

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P65
Unit cell:
a: 55.36Å b: 55.36Å c: 68.98Å
α: 90° β: 90° γ: 120°
R R work R free
0.175 0.173 0.199
Expression system: Escherichia coli