› 5ksy

X-ray diffraction
2.48Å resolution

hMiro1 C-domain GDP Complex P41212 Crystal Form

Released:
DOI: 10.2210/pdb5ksy/pdb
PDB 5ksy coloured by chain and viewed from the front.
PDB 5ksy coloured by chain and viewed from the side.
PDB 5ksy coloured by chain and viewed from the top.
Source organism: Homo sapiens
Primary publication:
Structural insights into Parkin substrate lysine targeting from minimal Miro substrates.
Klosowiak JL, Park S, Smith KP, French ME, Focia PJ, Freymann DM, Rice SE
OpenAccess logo Sci Rep 6 33019 (2016)
PMID: 27605430

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitochondrial Rho GTPase 1 Chain: A
Molecule details ›
Chain: A
Length: 192 amino acids
Theoretical weight: 22.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8IXI2 (Residues: 411-592; Coverage: 29%)
  • Best match: Q8IXI2-5 (Residues: 411-581)
Gene names: ARHT1, RHOT1
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

1 bound ligand:
Ligand GDP 1 x GDP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P41212
Unit cell:
a: 51.9Å b: 51.9Å c: 151.06Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.271 0.266 0.315
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Mitophagy and Neurodegeneration: Between the Knowns and the Unknowns.
Jetto et al. (2022)
6 more