Function and Biology

Crystal structure of the human astrovirus 2 capsid protein spike in complex with a single chain variable fragment of an astrovirus neutralizing antibody at 3.24-A resolution

Source organisms:
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF12226
Domain description: Turkey astrovirus capsid protein
Occurring in:
  1. Capsid protein VP25
The deposited structure of PDB entry 5kov contains 8 copies of Pfam domain PF12226 (Turkey astrovirus capsid protein) in Capsid protein VP25. Showing 1 copy in chain H [auth G].

InterPro InterPro annotations
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. PL-2 scFv chain
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. PL-2 scFv chain
IPR003599
Domain description: Immunoglobulin subtype
Occurring in:
  1. PL-2 scFv chain
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. PL-2 scFv chain
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. PL-2 scFv chain
IPR022027
Domain description: Turkey astrovirus capsid protein
Occurring in:
  1. Capsid protein VP25

Structure domain

CATH CATH domain
2.60.40.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulins
Occurring in:
  1. PL-2 scFv chain
The deposited structure of PDB entry 5kov contains 12 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in PL-2 scFv chain. Showing 2 copies in chain G [auth I].