X-ray diffraction
2.1Å resolution

Human Histidine Triad Nucleotide Binding Protein 2 (hHint2) triciribine 5'-monoposphate catalytic product complex


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Adenosine 5'-monophosphoramidase HINT2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 142 amino acids
Theoretical weight: 15.22 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q9BX68 (Residues: 26-163; Coverage: 85%)
Gene name: HINT2
Sequence domains: HIT domain
Structure domains: HIT-like

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P212121
Unit cell:
a: 38.129Å b: 76.045Å c: 77.821Å
α: 90° β: 90° γ: 90°
R R work R free
0.174 0.171 0.224
Expression system: Escherichia coli