5km4

X-ray diffraction
1.4Å resolution

Human Histidine Triad Nucleotide Binding Protein 1 (hHint1)-5-Iodo-UMP complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Histidine triad nucleotide-binding protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 129 amino acids
Theoretical weight: 14.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P49773 (Residues: 1-126; Coverage: 100%)
Gene names: HINT, HINT1, PKCI1, PRKCNH1
Sequence domains: HIT domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: C2
Unit cell:
a: 78.852Å b: 46.309Å c: 63.817Å
α: 90° β: 93.98° γ: 90°
R-values:
R R work R free
0.177 0.175 0.2
Expression system: Escherichia coli