5kka

X-ray diffraction
1.75Å resolution

E. coli malate dehydrogenase with the inhibitor 6DHNAD

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Malate dehydrogenase Chains: A, B
Molecule details ›
Chains: A, B
Length: 312 amino acids
Theoretical weight: 32.37 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
  • Canonical: P61889 (Residues: 1-312; Coverage: 100%)
Gene names: JW3205, b3236, mdh
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand 6V0 2 x 6V0
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P212121
Unit cell:
a: 77.53Å b: 83.832Å c: 89.275Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.155 0.154 0.181
Expression system: Escherichia coli