› 5kic

X-ray diffraction
2.7Å resolution

Long-sought stabilization of berkelium(IV) in solution: An anomaly within the heavy actinide series

Released:
DOI: 10.2210/pdb5kic/pdb
PDB 5kic coloured by chain and viewed from the front.
PDB 5kic coloured by chain and viewed from the side.
PDB 5kic coloured by chain and viewed from the top.
Source organism: Homo sapiens
Primary publication:
Chelation and stabilization of berkelium in oxidation state +IV.
Deblonde GJ, Sturzbecher-Hoehne M, Rupert PB, An DD, Illy MC, Ralston CY, Brabec J, de Jong WA, Strong RK, Abergel RJ
Nat Chem 9 843-849 (2017)
PMID: 28837177

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neutrophil gelatinase-associated lipocalin Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 180 amino acids
Theoretical weight: 20.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P80188 (Residues: 21-198; Coverage: 100%)
Gene names: HNL, LCN2, NGAL
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

4 bound ligands:
Ligand CF 3 x CF
Ligand 4OL 3 x 4OL
Ligand CL 3 x CL
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: P41212
Unit cell:
a: 119.574Å b: 119.574Å c: 108.839Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.205 0.242
Expression system: Escherichia coli

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Citations

3 review citations

Transuranic Computational Chemistry.
Kaltsoyannis N. (2018)
2 more