› 5kb5

X-ray diffraction
1.8Å resolution

Crystal structure of the adenosine kinase from Mus musculus in complex with adenosine and adenosine-diphosphate

Released:
DOI: 10.2210/pdb5kb5/pdb
PDB entry 5kb5 coloured by chain, front view.
PDB entry 5kb5 coloured by chain, side view.
PDB entry 5kb5 coloured by chain, top view.
Source organism: Mus musculus
Entry authors: Oliveira RR, Neto RM, Polo CC, Tonoli CCC, Murakami MT, Franchini KG

Function and Biology Details

Reaction catalysed: 
ATP + adenosine = ADP + AMP
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157285 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenosine kinase Chain: A
Molecule details ›
Chain: A
Length: 363 amino acids
Theoretical weight: 40.63 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P55264 (Residues: 20-361; Coverage: 95%)
Gene name: Adk
Sequence domains: pfkB family carbohydrate kinase
Structure domains:

Ligands and Environments

7 bound ligands:
Ligand ADN 1 x ADN
Ligand ADP 1 x ADP
Ligand K 1 x K
Ligand CL 1 x CL
Ligand MG 2 x MG
Ligand PG4 2 x PG4
Ligand PO4 2 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LNLS BEAMLINE W01B-MX2
Spacegroup: P212121
Unit cell:
a: 49.264Å b: 73.559Å c: 84.33Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.167 0.166 0.2
Expression system: Escherichia coli

Quick links