X-ray diffraction
1.4Å resolution

1.4 A resolution structure of Helicobacter Pylori MTAN in complexed with p-ClPh-DADMe-ImmA


Function and Biology Details

Reactions catalysed:
6-amino-6-deoxyfutalosine + H(2)O = dehypoxanthine futalosine + adenine
5'-deoxyadenosine + H(2)O = 5-deoxy-D-ribose + adenine
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Aminodeoxyfutalosine nucleosidase Chain: A
Molecule details ›
Chain: A
Length: 230 amino acids
Theoretical weight: 24.98 KDa
Source organism: Helicobacter pylori J99
Expression system: Escherichia coli
  • Canonical: Q9ZMY2 (Residues: 2-230; Coverage: 100%)
Gene names: jhp_0082, mtn, mtnN
Sequence domains: Phosphorylase superfamily
Structure domains: Nucleoside phosphorylase domain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P3221
Unit cell:
a: 81.207Å b: 81.207Å c: 67.254Å
α: 90° β: 90° γ: 120°
R R work R free
0.14 0.139 0.17
Expression system: Escherichia coli