5k79

X-ray diffraction
1.6Å resolution

Structure and anti-HIV activity of CYT-CVNH, a new cyanovirin-n homolog

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CVNH domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 108 amino acids
Theoretical weight: 11.94 KDa
Source organism: Cyanothece sp. PCC 7424
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: B7KDN5 (Residues: 32-139; Coverage: 78%)
Gene name: PCC7424_1905
Sequence domains: CVNH domain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21212
Unit cell:
a: 93.84Å b: 74.396Å c: 36.499Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.203 0.202 0.233
Expression system: Escherichia coli BL21(DE3)