› 5k6v

X-ray diffraction
3.21Å resolution

Sidekick-1 immunoglobulin domains 1-4, crystal form 2

Released:
DOI: 10.2210/pdb5k6v/pdb
PDB entry 5k6v coloured by chain, front view.
PDB entry 5k6v coloured by chain, side view.
PDB entry 5k6v coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Molecular basis of sidekick-mediated cell-cell adhesion and specificity.
Goodman KM, Yamagata M, Jin X, Mannepalli S, Katsamba PS, Ahlsén G, Sergeeva AP, Honig B, Sanes JR, Shapiro L
Elife 5 (2016)
PMID: 27644106

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174839 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Protein sidekick-1 Chain: A
Molecule details ›
Chain: A
Length: 384 amino acids
Theoretical weight: 42.48 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q3UH53 (Residues: 78-459; Coverage: 17%)
Gene name: Sdk1
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
2 bound ligands:
Ligand NAG 1 x NAG
Ligand ZN 6 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4C
Spacegroup: P3221
Unit cell:
a: 158.189Å b: 158.189Å c: 53.525Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.209 0.207 0.244
Expression system: Homo sapiens

Quick links

Citations

5 review citations

Adhesion Protein Structure, Molecular Affinities, and Principles of Cell-Cell Recognition.
Honig et al. (2020)
4 more

1 mention without citation

Molecular basis of sidekick-mediated cell-cell adhesion and specificity.
Goodman et al. (2016)