5k1v

X-ray diffraction
2.9Å resolution

Crystal structure of Endoplasmic Reticulum aminopeptidase 2 (ERAP2) in complex with a diaminobenzoic acid derivative ligand.

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Endoplasmic reticulum aminopeptidase 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 967 amino acids
Theoretical weight: 111.58 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q6P179 (Residues: 1-960; Coverage: 100%)
Gene names: ERAP2, LRAP
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, MAN
3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P21
Unit cell:
a: 74.403Å b: 135.171Å c: 127.489Å
α: 90° β: 90.15° γ: 90°
R-values:
R R work R free
0.208 0.205 0.273
Expression system: Trichoplusia ni