Function and Biology

Structures of Streptococcus agalactiae GBS GAPDH in different enzymatic states

Source organism: Streptococcus agalactiae
Biochemical function: NAD binding
Biological process: glycolytic process
Cellular component: cytoplasm

Sequence families

Pfam Protein families (Pfam)
PF02800
Domain description: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
Occurring in:
  1. Glyceraldehyde-3-phosphate dehydrogenase
The deposited structure of PDB entry 5jye contains 4 copies of Pfam domain PF02800 (Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain) in Glyceraldehyde-3-phosphate dehydrogenase. Showing 1 copy in chain D.

PF00044
Domain description: Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
Occurring in:
  1. Glyceraldehyde-3-phosphate dehydrogenase
The deposited structure of PDB entry 5jye contains 4 copies of Pfam domain PF00044 (Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain) in Glyceraldehyde-3-phosphate dehydrogenase. Showing 1 copy in chain D.

InterPro InterPro annotations
IPR020831
Domain description: Glyceraldehyde/Erythrose phosphate dehydrogenase family
Occurring in:
  1. Glyceraldehyde-3-phosphate dehydrogenase
IPR020828
Domain description: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain
Occurring in:
  1. Glyceraldehyde-3-phosphate dehydrogenase
IPR020829
Domain description: Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain
Occurring in:
  1. Glyceraldehyde-3-phosphate dehydrogenase
IPR020830
Domain description: Glyceraldehyde 3-phosphate dehydrogenase, active site
Occurring in:
  1. Glyceraldehyde-3-phosphate dehydrogenase
IPR006424
Domain description: Glyceraldehyde-3-phosphate dehydrogenase, type I
Occurring in:
  1. Glyceraldehyde-3-phosphate dehydrogenase
IPR036291
Domain description: NAD(P)-binding domain superfamily
Occurring in:
  1. Glyceraldehyde-3-phosphate dehydrogenase
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. Glyceraldehyde-3-phosphate dehydrogenase

Structure domains

CATH CATH domains
3.40.50.720
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: NAD(P)-binding Rossmann-like Domain
Occurring in:
  1. Glyceraldehyde-3-phosphate dehydrogenase
The deposited structure of PDB entry 5jye contains 4 copies of CATH domain 3.40.50.720 (Rossmann fold) in Glyceraldehyde-3-phosphate dehydrogenase. Showing 1 copy in chain D.
3.30.360.10
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Dihydrodipicolinate Reductase; domain 2
Homology: Dihydrodipicolinate Reductase; domain 2
Occurring in:
  1. Glyceraldehyde-3-phosphate dehydrogenase
The deposited structure of PDB entry 5jye contains 4 copies of CATH domain 3.30.360.10 (Dihydrodipicolinate Reductase; domain 2) in Glyceraldehyde-3-phosphate dehydrogenase. Showing 1 copy in chain D.