X-ray diffraction
1.6Å resolution

Crystal structure of laccase from Thermus thermophilus HB27 (Cu(II)-cyclophanes, 5 min)

Source organism: Thermus thermophilus HB27
Entry authors: Diaz-Vilchis A, Ruiz-Arellano RR, Rosas-Benitez E, Rudino-Pinera E

Function and Biology Details

Reaction catalysed:
4 benzenediol + O(2) = 4 benzosemiquinone + 2 H(2)O
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Laccase Chain: A
Molecule details ›
Chain: A
Length: 439 amino acids
Theoretical weight: 48.79 KDa
Source organism: Thermus thermophilus HB27
Expression system: Escherichia coli
  • Canonical: Q72HW2 (Residues: 24-462; Coverage: 95%)
Gene name: TT_C1370
Sequence domains:
Structure domains: Cupredoxins - blue copper proteins

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X6A
Spacegroup: C2221
Unit cell:
a: 93.44Å b: 109.86Å c: 96.05Å
α: 90° β: 90° γ: 90°
R R work R free
0.151 0.15 0.176
Expression system: Escherichia coli