X-ray diffraction
2.6Å resolution

MraY tunicamycin complex


Function and Biology Details

Reaction catalysed:
UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate = UMP + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Phospho-N-acetylmuramoyl-pentapeptide-transferase Chain: A
Molecule details ›
Chain: A
Length: 376 amino acids
Theoretical weight: 40.95 KDa
Source organism: [Clostridium] bolteae 90A9
Expression system: Escherichia coli
  • Canonical: R0BTE9 (Residues: 1-322; Coverage: 100%)
Gene names: HMPREF1085_00623, mraY
Sequence domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: C2221
Unit cell:
a: 92.64Å b: 105.54Å c: 134.96Å
α: 90° β: 90° γ: 90°
R R work R free
0.228 0.226 0.252
Expression system: Escherichia coli