Function and Biology

Structure of the F-actin-tropomyosin complex (Reprocessed)

Source organisms:
Biochemical function: cytoskeletal motor activator activity
Biological process: mesenchyme migration
Cellular component: skeletal muscle myofibril

Sequence family

Pfam Protein family (Pfam)
PF00022
Domain description: Actin
Occurring in:
  1. Actin, alpha skeletal muscle
The deposited structure of PDB entry 5jlf contains 5 copies of Pfam domain PF00022 (Actin) in Actin, alpha skeletal muscle. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR004000
Domain description: Actin family
Occurring in:
  1. Actin, alpha skeletal muscle
IPR004001
Domain description: Actin, conserved site
Occurring in:
  1. Actin, alpha skeletal muscle
IPR043129
Domain description: ATPase, nucleotide binding domain
Occurring in:
  1. Actin, alpha skeletal muscle
IPR020902
Domain description: Actin/actin-like conserved site
Occurring in:
  1. Actin, alpha skeletal muscle

Structure domains

CATH CATH domains
3.30.420.40
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Nucleotidyltransferase; domain 5
Homology: Nucleotidyltransferase; domain 5
Occurring in:
  1. Actin, alpha skeletal muscle
The deposited structure of PDB entry 5jlf contains 10 copies of CATH domain 3.30.420.40 (Nucleotidyltransferase; domain 5) in Actin, alpha skeletal muscle. Showing 2 copies in chain A.
3.90.640.10
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Actin; Chain A, domain 4
Homology: Actin; Chain A, domain 4
Occurring in:
  1. Actin, alpha skeletal muscle
The deposited structure of PDB entry 5jlf contains 5 copies of CATH domain 3.90.640.10 (Actin; Chain A, domain 4) in Actin, alpha skeletal muscle. Showing 1 copy in chain A.
2.30.36.70
Class: Mainly Beta
Architecture: Roll
Topology: Actin; Chain A, domain 2
Homology: Actin; Chain A, domain 2
Occurring in:
  1. Actin, alpha skeletal muscle
The deposited structure of PDB entry 5jlf contains 5 copies of CATH domain 2.30.36.70 (Actin; Chain A, domain 2) in Actin, alpha skeletal muscle. Showing 1 copy in chain A.