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Crystal structure of human IZUMO1-JUNO complex (crystal form 3)

Source organism: Homo sapiens
Biochemical function: signaling receptor binding
Biological process: sperm-egg recognition
Cellular component: membrane

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF03024
Domain description: Folate receptor family
Occurring in:
  1. Sperm-egg fusion protein Juno
The deposited structure of PDB entry 5jke contains 2 copies of Pfam domain PF03024 (Folate receptor family) in Sperm-egg fusion protein Juno. Showing 1 copy in chain B.

PF16706
Domain description: Izumo-like Immunoglobulin domain
Occurring in:
  1. Izumo sperm-egg fusion protein 1
The deposited structure of PDB entry 5jke contains 2 copies of Pfam domain PF16706 (Izumo-like Immunoglobulin domain) in Izumo sperm-egg fusion protein 1. Showing 1 copy in chain A.

PF15005
Domain description: Izumo sperm-egg fusion, Ig domain-associated
Occurring in:
  1. Izumo sperm-egg fusion protein 1
The deposited structure of PDB entry 5jke contains 2 copies of Pfam domain PF15005 (Izumo sperm-egg fusion, Ig domain-associated) in Izumo sperm-egg fusion protein 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR018143
Domain description: Folate receptor-like
Occurring in:
  1. Sperm-egg fusion protein Juno
IPR004269
Domain description: Folate receptor
Occurring in:
  1. Sperm-egg fusion protein Juno
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. Izumo sperm-egg fusion protein 1
IPR032699
Domain description: Izumo protein, immunoglobulin domain
Occurring in:
  1. Izumo sperm-egg fusion protein 1
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. Izumo sperm-egg fusion protein 1
IPR032700
Domain description: Izumo sperm-egg fusion protein 1
Occurring in:
  1. Izumo sperm-egg fusion protein 1
IPR029389
Domain description: Izumo sperm-egg fusion protein
Occurring in:
  1. Izumo sperm-egg fusion protein 1

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