PDBe 5jjz

X-ray diffraction
2Å resolution

Chromo domain of human Chromodomain Protein, Y-Like 2

Released:
Source organism: Homo sapiens
Entry authors: DONG A, DOMBROVSKI L, LOPPNAU P, TEMPEL W, Bountra C, Arrowsmith CH, Edwards AM, MIN J, WU H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero tetramer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Chromodomain Y-like protein 2 Chain: A
Molecule details ›
Chain: A
Length: 83 amino acids
Theoretical weight: 10.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8N8U2 (Residues: 2-66; Coverage: 13%)
Gene name: CDYL2
Sequence domains: Chromo (CHRromatin Organisation MOdifier) domain
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Histone H1.4 Chain: B
Molecule details ›
Chain: B
Length: 13 amino acids
Theoretical weight: 1.44 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P10412 (Residues: 21-32; Coverage: 6%)
Gene names: H1F4, HIST1H1E

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P6122
Unit cell:
a: 57.962Å b: 57.962Å c: 98.824Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.232 0.23 0.26
Expression systems:
  • Escherichia coli
  • Not provided