X-ray diffraction
1.85Å resolution

Crystal structure of rat coronavirus strain New-Jersey Hemagglutinin-Esterase in complex with 4N-acetyl sialic acid


Function and Biology Details

Reaction catalysed:
N-acetyl-O-acetylneuraminate + H(2)O = N-acetylneuraminate + acetate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Hemagglutinin-esterase Chain: A
Molecule details ›
Chain: A
Length: 388 amino acids
Theoretical weight: 43.61 KDa
Source organism: Rat coronavirus
Expression system: Homo sapiens
  • Canonical: Q3HS77 (Residues: 22-400; Coverage: 87%)
Gene name: HE
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: C2221
Unit cell:
a: 57.09Å b: 184.59Å c: 78.08Å
α: 90° β: 90° γ: 90°
R R work R free
0.185 0.184 0.2
Expression system: Homo sapiens