PDBe 5jf3

X-ray diffraction
1.6Å resolution

Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor AT018

Released:

Function and Biology Details

Reaction catalysed:
Formyl-L-methionyl peptide + H(2)O = formate + methionyl peptide
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptide deformylase Chain: A
Molecule details ›
Chain: A
Length: 204 amino acids
Theoretical weight: 22.89 KDa
Source organism: Streptococcus agalactiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8E378 (Residues: 1-204; Coverage: 100%)
Gene names: def, gbs1883
Sequence domains: Polypeptide deformylase
Structure domains: Peptide deformylase

Ligands and Environments


1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P212121
Unit cell:
a: 41.07Å b: 65.49Å c: 88.79Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.187 0.186 0.214
Expression system: Escherichia coli BL21(DE3)