› 5jcr

X-ray diffraction
1.7Å resolution

Crystal structure of the FimH lectin domain from E.coli K12 in complex with methyl alpha-D-mannopyrannoside in spacegroup P212121

Released:
DOI: 10.2210/pdb5jcr/pdb
PDB 5jcr coloured by chain and viewed from the front.
PDB 5jcr coloured by chain and viewed from the side.
PDB 5jcr coloured by chain and viewed from the top.
Source organism: Escherichia coli K-12
Entry authors: Jakob RP, Rabbani S, Ernst B, Maier T

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Type 1 fimbrin D-mannose specific adhesin Chains: A, B
Molecule details ›
Chains: A, B
Length: 158 amino acids
Theoretical weight: 16.92 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P08191 (Residues: 22-179; Coverage: 57%)
Gene names: JW4283, b4320, fimH
Sequence domains: FimH, mannose binding
Structure domains: Fimbrial-type adhesion domain

Ligands and Environments

1 bound ligand:
Ligand MMA 2 x MMA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P212121
Unit cell:
a: 62.98Å b: 68.95Å c: 95.6Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.209 0.23
Expression system: Escherichia coli BL21(DE3)

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