PDBe 5jcg

X-ray diffraction
2.8Å resolution

Structure of Human Peroxiredoxin 3 as three stacked rings

Released:

Function and Biology Details

Reaction catalysed:
2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo 36-mer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin-dependent peroxide reductase, mitochondrial Chains: A, B, C, D, E, F, G, H, I
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I
Length: 201 amino acids
Theoretical weight: 22.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P30048 (Residues: 62-256; Coverage: 76%)
Gene names: AOP1, PRDX3
Sequence domains:
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: I222
Unit cell:
a: 133.188Å b: 168.73Å c: 221.55Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.185 0.183 0.229
Expression system: Escherichia coli BL21(DE3)