Structure analysis

Architecture of loose respirasome

Electron Microscopy
6.7Å resolution
Source organism: Ovis aries
Assembly composition:
hetero 89-mer (preferred)
Entry contents: 74 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero 89-mer
PDBe Complex ID: PDB-CPX-105818

Macromolecules

Chain: A
Length: 102 amino acids
Theoretical weight: 8.7 KDa
Source organism: Ovis aries

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Chain: B
Length: 154 amino acids
Theoretical weight: 13.2 KDa
Source organism: Ovis aries

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Chain: C
Length: 194 amino acids
Theoretical weight: 16.53 KDa
Source organism: Ovis aries

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Chain: D
Length: 384 amino acids
Theoretical weight: 32.7 KDa
Source organism: Ovis aries

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Chain: E
Length: 189 amino acids
Theoretical weight: 16.17 KDa
Source organism: Ovis aries

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Chain: F
Length: 429 amino acids
Theoretical weight: 36.6 KDa
Source organism: Ovis aries

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Chain: G
Length: 652 amino acids
Theoretical weight: 55.76 KDa
Source organism: Ovis aries
InterPro:

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Chain: H
Length: 297 amino acids
Theoretical weight: 25.29 KDa
Source organism: Ovis aries

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Chain: I
Length: 171 amino acids
Theoretical weight: 14.72 KDa
Source organism: Ovis aries

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Chain: J
Length: 171 amino acids
Theoretical weight: 14.57 KDa
Source organism: Ovis aries

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Chain: K
Length: 93 amino acids
Theoretical weight: 7.93 KDa
Source organism: Ovis aries

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Chain: L
Length: 575 amino acids
Theoretical weight: 48.95 KDa
Source organism: Ovis aries

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Chain: M
Length: 455 amino acids
Theoretical weight: 38.74 KDa
Source organism: Ovis aries

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Chain: N
Length: 345 amino acids
Theoretical weight: 29.38 KDa
Source organism: Ovis aries

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Chain: O
Length: 104 amino acids
Theoretical weight: 8.87 KDa
Source organism: Ovis aries

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Chain: P
Length: 85 amino acids
Theoretical weight: 7.25 KDa
Source organism: Ovis aries

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Chain: Q
Length: 66 amino acids
Theoretical weight: 5.63 KDa
Source organism: Ovis aries

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Chains: S, d
Length: 80 amino acids
Theoretical weight: 6.83 KDa
Source organism: Ovis aries

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Chain: T
Length: 53 amino acids
Theoretical weight: 4.53 KDa
Source organism: Ovis aries

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Chain: U
Length: 96 amino acids
Theoretical weight: 8.19 KDa
Source organism: Ovis aries

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Chain: V
Length: 112 amino acids
Theoretical weight: 9.55 KDa
Source organism: Ovis aries

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Chain: W
Length: 103 amino acids
Theoretical weight: 8.78 KDa
Source organism: Ovis aries

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Chain: X
Length: 309 amino acids
Theoretical weight: 26.32 KDa
Source organism: Ovis aries

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Chain: Y
Length: 322 amino acids
Theoretical weight: 27.42 KDa
Source organism: Ovis aries

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Chain: Z
Length: 119 amino acids
Theoretical weight: 10.15 KDa
Source organism: Ovis aries

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Chain: a
Length: 111 amino acids
Theoretical weight: 9.46 KDa
Source organism: Ovis aries

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Chain: b
Length: 92 amino acids
Theoretical weight: 7.85 KDa
Source organism: Ovis aries

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Chain: c
Length: 79 amino acids
Theoretical weight: 6.74 KDa
Source organism: Ovis aries

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Chain: e
Length: 55 amino acids
Theoretical weight: 4.7 KDa
Source organism: Ovis aries

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Chain: f
Length: 59 amino acids
Theoretical weight: 5.04 KDa
Source organism: Ovis aries

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Chain: g
Length: 130 amino acids
Theoretical weight: 11.08 KDa
Source organism: Ovis aries

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Chains: 9, h, z
Length: 63 amino acids
Theoretical weight: 5.38 KDa
Source organism: Ovis aries

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Chain: i
Length: 70 amino acids
Theoretical weight: 5.98 KDa
Source organism: Ovis aries

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Chain: j
Length: 44 amino acids
Theoretical weight: 3.76 KDa
Source organism: Ovis aries

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Chain: k
Length: 83 amino acids
Theoretical weight: 7.08 KDa
Source organism: Ovis aries

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Chain: 0
Length: 36 amino acids
Theoretical weight: 3.08 KDa
Source organism: Ovis aries

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Chain: y
Length: 46 amino acids
Theoretical weight: 3.93 KDa
Source organism: Ovis aries

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Chains: AA, AL
Length: 446 amino acids
Theoretical weight: 49.39 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5Q5G6 (Residues: 35-483; Coverage: 92%)
Gene name: LOC101110095
Pfam:
InterPro:

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Chains: AB, AM
Length: 423 amino acids
Theoretical weight: 45.19 KDa
Source organism: Ovis aries
InterPro:

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Chains: AD, AO
Length: 241 amino acids
Theoretical weight: 27.32 KDa
Source organism: Ovis aries
InterPro:

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Chains: AF, AQ
Length: 105 amino acids
Theoretical weight: 12.95 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5P642 (Residues: 5-109; Coverage: 96%)
Pfam: Ubiquinol-cytochrome C reductase complex 14kD subunit
InterPro:

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Chains: AG, AR
Length: 75 amino acids
Theoretical weight: 8.88 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5PUP9 (Residues: 2-76; Coverage: 92%)
Gene name: LOC101121420
Pfam: UcrQ family
InterPro:

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Chain: BD
Length: 144 amino acids
Theoretical weight: 16.9 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5PPE8 (Residues: 26-169; Coverage: 85%)
Gene name: LOC101105179
Pfam: Cytochrome c oxidase subunit IV
InterPro:

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Chain: BE
Length: 105 amino acids
Theoretical weight: 12.08 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5NXT8 (Residues: 17-121; Coverage: 87%)
Pfam: Cytochrome c oxidase subunit Va
InterPro:

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Chain: BP
Length: 98 amino acids
Theoretical weight: 10.67 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5PW27 (Residues: 46-143; Coverage: 69%)
Gene name: LOC101110664
Pfam: Cytochrome c oxidase subunit Vb
InterPro:

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Chain: BH
Length: 79 amino acids
Theoretical weight: 9.41 KDa
Source organism: Ovis aries
InterPro:

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Chain: BI
Length: 73 amino acids
Theoretical weight: 8.47 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5PXG3 (Residues: 2-74; Coverage: 99%)
Pfam: Cytochrome c oxidase subunit VIc
InterPro:

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Chain: BJ
Length: 58 amino acids
Theoretical weight: 6.54 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5P5H0 (Residues: 20-77; Coverage: 74%)
Gene name: LOC101121285
Pfam: Cytochrome c oxidase subunit VII
InterPro:

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Chain: BK
Length: 49 amino acids
Theoretical weight: 5.46 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5QE72 (Residues: 35-83; Coverage: 58%)
Pfam: Cytochrome C oxidase chain VIIB
InterPro:

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Chain: BL
Length: 46 amino acids
Theoretical weight: 5.36 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: A0A6P7E5B2 (Residues: 18-63; Coverage: 73%)
Gene name: LOC121816305
Pfam: Cytochrome c oxidase subunit VIIc
InterPro:

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Chain: BM
Length: 43 amino acids
Theoretical weight: 4.74 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5PFK9 (Residues: 25-69; Coverage: 60%)
Pfam: Cytochrome oxidase c subunit VIII
InterPro:

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