Function and Biology Details
Reaction catalysed:
4 ferrocytochrome c + O(2) + 8 H(+)(Side 1) = 4 ferricytochrome c + 4 H(2)O(Side 2)
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero 89-mer (preferred)
Entry contents:
74 distinct polypeptide molecules
Macromolecules (74 distinct):
COMPLEX I ND3
Chain: A
COMPLEX I PSST/NDUFS7
Chain: B
COMPLEX I 30KDA/NDUFS3
Chain: C
COMPLEX I 49KDA/NDUFS2
Chain: D
COMPLEX I 24KDA/NDUFV2
Chain: E
COMPLEX I 51KDA/NDUFV1
Chain: F
COMPLEX I 75KDA/NDUFS1
Chain: G
COMPLEX I ND1
Chain: H
COMPLEX I TYKY/NDUFS8
Chain: I
COMPLEX I ND6
Chain: J
COMPLEX I ND4L
Chain: K
COMPLEX I ND5
Chain: L
COMPLEX I ND4
Chain: M
COMPLEX I ND2
Chain: N
COMPLEX I 18KDA/NDUFS6
Chain: O
COMPLEX I 13KDA/NDUFS6
Chain: P
COMPLEX I 15KDA/NDUFS5
Chain: Q
COMPLEX I MWFE/NDUFA1
Chain: R
COMPLEX I B8/NDUFA2
Chains: S, d
COMPLEX I B9/NDUFA3
Chain: T
COMPLEX I B13/NDUFA5
Chain: U
COMPLEX I B14/NDUFA6
Chain: V
COMPLEX I PGIV/NDUFA8
Chain: W
COMPLEX I 39KDA/NDUFA9
Chain: X
COMPLEX I 42KDA/NDUFA10
Chain: Y
COMPLEX I B14.7/NDUFA11
Chain: Z
COMPLEX I B17.2/NDUFA12
Chain: a
COMPLEX I B16.6/NDUFA13
Chain: b
COMPLEX I SDAP/NDUFAB1
Chain: c
COMPLEX I SDAP/NDUFAB1
Chain: e
COMPLEX I SDAP/NDUFAB1
Chain: f
COMPLEX I B15/NDUFB4
Chain: g
COMPLEX I B18/NDUFB7
Chains: 9, h, z
COMPLEX I B22/NDUFB9
Chain: i
COMPLEX I PDSW/NDUFB10
Chain: j
COMPLEX I ESSS/NDUFB11
Chain: k
COMPLEX I KFYI/NDUFC1
Chain: 0
COMPLEX I B14.5B/NDUFC2
Chain: 1
COMPLEX I UNKNOWN SUBUNIT FRAGMENT 1
Chain: 2
COMPLEX I UNKNOWN SUBUNIT FRAGMENT 2
Chains: 3, 4
COMPLEX I UNKNOWN SUBUNIT FRAGMENT 3
Chain: 5
COMPLEX I UNKNOWN SUBUNIT FRAGMENT 4
Chain: 6
COMPLEX I UNKNOWN SUBUNIT FRAGMENT 5
Chain: 7
COMPLEX I UNKNOWN SUBUNIT FRAGMENT 6
Chain: 8
COMPLEX I UNKNOWN SUBUNIT FRAGMENT 11
Chain: y
COMPLEX I UNKNOWN SUBUNIT FRAGMENT 12
Chain: x
COMPLEX I UNKNOWN SUBUNIT FRAGMENT 13
Chain: w
COMPLEX I UNKNOWN SUBUNIT FRAGMENT 14
Chain: v
COMPLEX I UNKNOWN SUBUNIT FRAGMENT 15
Chain: u
COMPLEX I UNKNOWN SUBUNIT FRAGMENT 16
Chain: t
Cytochrome b-c1 complex subunit 1, mitochondrial
Chains: AA, AL
Molecule details ›
Chains: AA, AL
Length: 449 amino acids
Theoretical weight: 49.65 KDa
Source organism: Ovis aries
UniProt:
Sequence domains:
Length: 449 amino acids
Theoretical weight: 49.65 KDa
Source organism: Ovis aries
UniProt:
- Canonical:
W5Q5G6 (Residues: 35-483; Coverage: 93%)
Sequence domains:
COMPLEX III SUBUNIT 2 / CORE 2
Chains: AB, AM
Cytochrome b
Chains: AC, AN
Molecule details ›
COMPLEX III SUBUNIT 4 / CYTOCHROME C1
Chains: AD, AO
Cytochrome b-c1 complex subunit Rieske, mitochondrial
Chains: AE, AP
Cytochrome b-c1 complex subunit 7
Chains: AF, AQ
Molecule details ›
Chains: AF, AQ
Length: 105 amino acids
Theoretical weight: 12.95 KDa
Source organism: Ovis aries
UniProt:
Length: 105 amino acids
Theoretical weight: 12.95 KDa
Source organism: Ovis aries
UniProt:
- Canonical:
W5P642 (Residues: 5-109; Coverage: 96%)
Cytochrome b-c1 complex subunit 8
Chains: AG, AR
Molecule details ›
Chains: AG, AR
Length: 75 amino acids
Theoretical weight: 8.88 KDa
Source organism: Ovis aries
UniProt:
Sequence domains: UcrQ family
Length: 75 amino acids
Theoretical weight: 8.88 KDa
Source organism: Ovis aries
UniProt:
- Canonical:
W5PUP9 (Residues: 2-76; Coverage: 92%)
Sequence domains: UcrQ family
Cytochrome b-c1 complex subunit 6
Chains: AH, AS
Cytochrome b-c1 complex subunit Rieske, mitochondrial
Chains: AI, AT
COMPLEX III SUBUNIT 9 / 7.2KDA
Chains: AJ, AU
COMPLEX III SUBUNIT 10 / 6.4KDA
Chains: AK, AV
Cytochrome c oxidase subunit 1
Chain: BN
Molecule details ›
Chain: BN
Length: 514 amino acids
Theoretical weight: 57.08 KDa
Source organism: Ovis aries
UniProt:
Sequence domains: Cytochrome C and Quinol oxidase polypeptide I
Length: 514 amino acids
Theoretical weight: 57.08 KDa
Source organism: Ovis aries
UniProt:
- Canonical:
O78749 (Residues: 1-514; Coverage: 100%)
Sequence domains: Cytochrome C and Quinol oxidase polypeptide I
Cytochrome c oxidase subunit 2
Chain: BO
Molecule details ›
Cytochrome c oxidase subunit 3
Chain: BC
Molecule details ›
Chain: BC
Length: 259 amino acids
Theoretical weight: 29.66 KDa
Source organism: Ovis aries
UniProt:
Sequence domains: Cytochrome c oxidase subunit III
Length: 259 amino acids
Theoretical weight: 29.66 KDa
Source organism: Ovis aries
UniProt:
- Canonical:
O21619 (Residues: 3-261; Coverage: 99%)
Sequence domains: Cytochrome c oxidase subunit III
Cytochrome c oxidase subunit 4
Chain: BD
Molecule details ›
Chain: BD
Length: 144 amino acids
Theoretical weight: 16.9 KDa
Source organism: Ovis aries
UniProt:
Sequence domains: Cytochrome c oxidase subunit IV
Length: 144 amino acids
Theoretical weight: 16.9 KDa
Source organism: Ovis aries
UniProt:
- Canonical:
W5PPE8 (Residues: 26-169; Coverage: 85%)
Sequence domains: Cytochrome c oxidase subunit IV
Cytochrome c oxidase subunit 5A, mitochondrial
Chain: BE
Molecule details ›
Chain: BE
Length: 105 amino acids
Theoretical weight: 12.08 KDa
Source organism: Ovis aries
UniProt:
Length: 105 amino acids
Theoretical weight: 12.08 KDa
Source organism: Ovis aries
UniProt:
- Canonical:
W5NXT8 (Residues: 17-121; Coverage: 87%)
Cytochrome c oxidase subunit 5B, mitochondrial
Chain: BP
Molecule details ›
Chain: BP
Length: 98 amino acids
Theoretical weight: 10.67 KDa
Source organism: Ovis aries
UniProt:
Sequence domains: Cytochrome c oxidase subunit Vb
Length: 98 amino acids
Theoretical weight: 10.67 KDa
Source organism: Ovis aries
UniProt:
- Canonical:
W5PW27 (Residues: 46-143; Coverage: 69%)
Sequence domains: Cytochrome c oxidase subunit Vb
Cytochrome c oxidase subunit 6A, mitochondrial
Chain: BG
COMPLEX IV COX6B1
Chain: BH
Cytochrome c oxidase subunit 6C
Chain: BI
Molecule details ›
Chain: BI
Length: 73 amino acids
Theoretical weight: 8.47 KDa
Source organism: Ovis aries
UniProt:
Length: 73 amino acids
Theoretical weight: 8.47 KDa
Source organism: Ovis aries
UniProt:
- Canonical:
W5PXG3 (Residues: 2-74; Coverage: 99%)
Cytochrome c oxidase subunit 7A1, mitochondrial
Chain: BJ
Molecule details ›
Chain: BJ
Length: 58 amino acids
Theoretical weight: 6.54 KDa
Source organism: Ovis aries
UniProt:
Sequence domains: Cytochrome c oxidase subunit VII
Length: 58 amino acids
Theoretical weight: 6.54 KDa
Source organism: Ovis aries
UniProt:
- Canonical:
W5P5H0 (Residues: 20-77; Coverage: 74%)
Sequence domains: Cytochrome c oxidase subunit VII
Cytochrome c oxidase subunit 7B, mitochondrial
Chain: BK
Molecule details ›
Chain: BK
Length: 49 amino acids
Theoretical weight: 5.46 KDa
Source organism: Ovis aries
UniProt:
Length: 49 amino acids
Theoretical weight: 5.46 KDa
Source organism: Ovis aries
UniProt:
- Canonical:
W5QE72 (Residues: 35-83; Coverage: 58%)
Cytochrome c oxidase subunit 7C, mitochondrial
Chain: BL
Molecule details ›
Chain: BL
Length: 46 amino acids
Theoretical weight: 5.36 KDa
Source organism: Ovis aries
UniProt:
Sequence domains: Cytochrome c oxidase subunit VIIc
Length: 46 amino acids
Theoretical weight: 5.36 KDa
Source organism: Ovis aries
UniProt:
- Canonical:
A0A6P7E5B2 (Residues: 18-63; Coverage: 73%)
Sequence domains: Cytochrome c oxidase subunit VIIc
Cytochrome c oxidase subunit 8
Chain: BM
Molecule details ›
Chain: BM
Length: 43 amino acids
Theoretical weight: 4.74 KDa
Source organism: Ovis aries
UniProt:
Length: 43 amino acids
Theoretical weight: 4.74 KDa
Source organism: Ovis aries
UniProt:
- Canonical:
W5PFK9 (Residues: 25-69; Coverage: 60%)