X-ray diffraction
2.2Å resolution

Zika Virus Non-structural Protein NS1

Source organism: Zika virus

Function and Biology Details

Reactions catalysed:
NTP + H(2)O = NDP + phosphate
ATP + H(2)O = ADP + phosphate
Selective hydrolysis of -Xaa-Xaa-|-Yaa- bonds in which each of the Xaa can be either Arg or Lys and Yaa can be either Ser or Ala.
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Genome polyprotein Chains: A, B
Molecule details ›
Chains: A, B
Length: 181 amino acids
Theoretical weight: 20.77 KDa
Source organism: Zika virus
Expression system: Escherichia coli
  • Canonical: A0A109PRQ3 (Residues: 966-1146; Coverage: 5%)
Sequence domains: Flavivirus non-structural Protein NS1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: C2221
Unit cell:
a: 63.868Å b: 103.755Å c: 114.843Å
α: 90° β: 90° γ: 90°
R R work R free
0.207 0.205 0.246
Expression system: Escherichia coli