5ikc

X-ray diffraction
2.06Å resolution

X-RAY STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN in complex with FAB

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
MAb 6H10 light chain Chains: A, L
Molecule details ›
Chains: A, L
Length: 213 amino acids
Theoretical weight: 23.51 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
Structure domains: Immunoglobulins
Ighg protein Chains: B, H
Molecule details ›
Chains: B, H
Length: 215 amino acids
Theoretical weight: 22.8 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
Structure domains: Immunoglobulins
Neuronal migration protein doublecortin Chains: M, N
Molecule details ›
Chains: M, N
Length: 90 amino acids
Theoretical weight: 10.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O43602 (Residues: 52-140; Coverage: 24%)
Gene names: DBCN, DCX, LISX
Sequence domains: Doublecortin
Structure domains: Doublecortin domain

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P21
Unit cell:
a: 66.858Å b: 110.399Å c: 75.092Å
α: 90° β: 106.54° γ: 90°
R-values:
R R work R free
0.201 0.198 0.265
Expression system: Escherichia coli