› 5iie

X-ray diffraction
2.8Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
antibody DH501 FabH chain Chains: A, H
Molecule details ›
Chains: A, H
Length: 230 amino acids
Theoretical weight: 24.64 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
antibody DH501 light chain Chains: B, L
Molecule details ›
Chains: B, L
Length: 216 amino acids
Theoretical weight: 22.86 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-BM
Spacegroup: P212121
Unit cell:
a: 76.113Å b: 89.028Å c: 132.131Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.206 0.273
Expression system: Homo sapiens

Quick links

Citations

8 review citations

Targeting the N332-supersite of the HIV-1 envelope for vaccine design.
Moyo et al. (2020)
7 more

2 mentions without citation

Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates.
Saunders et al. (2017)
1 more