5ih7

X-ray diffraction
2.4Å resolution

Acetylcholinesterase of Torpedo californica in complex with the N-methyl-indoxylacetate hydrolysis products

Released:
Source organism: Tetronarce californica
Entry authors: Pesaresi A, Lamba D

Function and Biology Details

Reaction catalysed:
Acetylcholine + H(2)O = choline + acetate
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Acetylcholinesterase Chain: A
Molecule details ›
Chain: A
Length: 534 amino acids
Theoretical weight: 60.45 KDa
Source organism: Tetronarce californica
UniProt:
  • Canonical: P04058 (Residues: 23-556; Coverage: 95%)
Gene name: ache
Sequence domains: Carboxylesterase family
Structure domains: Rossmann fold

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELETTRA BEAMLINE 5.2R
Spacegroup: P3121
Unit cell:
a: 111.99Å b: 111.99Å c: 137.05Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.172 0.17 0.207