X-ray diffraction
3.6Å resolution

Crystal structure of C-terminal variant 1 of Chaetomium thermophilum acetyl-CoA carboxylase


Function and Biology Details

Reactions catalysed:
ATP + acetyl-CoA + HCO(3)(-) = ADP + phosphate + malonyl-CoA
ATP + [biotin carboxyl-carrier protein]-biotin-N(6)-L-lysine + hydrogencarbonate- = ADP + phosphate + [biotin carboxyl-carrier protein]-carboxybiotin-N(6)-L-lysine
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Acetyl-CoA carboxylase-like protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 1179 amino acids
Theoretical weight: 133.45 KDa
Source organism: Chaetomium thermophilum var. thermophilum DSM 1495
Expression system: Spodoptera frugiperda
  • Canonical: G0S3L5 (Residues: 1114-2264; Coverage: 50%)
Gene name: CTHT_0021690
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P212121
Unit cell:
a: 97.66Å b: 165.34Å c: 219.23Å
α: 90° β: 90° γ: 90°
R R work R free
0.205 0.203 0.243
Expression system: Spodoptera frugiperda