X-ray diffraction
3.7Å resolution

The structure of the eukaryotic purine/H+ symporter, UapA, in complex with Xanthine


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Uric acid-xanthine permease Chains: A, B
Molecule details ›
Chains: A, B
Length: 574 amino acids
Theoretical weight: 61.2 KDa
Source organism: Aspergillus nidulans FGSC A4
Expression system: Saccharomyces cerevisiae
  • Canonical: Q07307 (Residues: 1-574; Coverage: 100%)
Gene names: AN6932, uapA
Sequence domains: Permease family

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P21
Unit cell:
a: 75.09Å b: 173.83Å c: 82.39Å
α: 90° β: 111.11° γ: 90°
R R work R free
0.298 0.296 0.327
Expression system: Saccharomyces cerevisiae